Forskningsanslag

Dr Cathereine Arden

Type 2 Diabetes develops when the pancreas fail to release enough insulin to meet demand due to both decreased function of pancreatic beta-cells and through loss of beta-cell number. The current study aims to investigate how an enzyme important in regulating the function of insulin secretion (glucokinase) binds to a protein important in regulating beta-cell number (BAD) and will determine whether communication between these two proteins provides a link between the regulation of beta-cell function and beta-cell mass. Understanding these mechanisms is essential to enable the development of new treatments for Type 2 Diabetes.  
Källa: http://www.drwf.org.uk/Research/FundedResearch/tabid/358/ItemId/84/Default.aspx